"Would it be a problem to match a Class D amp with the Class B amp that is built into the Vandy Quatro's?"
It will work with no problems, but its not an optimal match for Vandersteen. If you find that you want to build a system around class D amps, You would probably be happier with a different speaker. Probably the best way to pick a system is to start with a must have, and then build around that. So, for example, class D is your must have, build a system around that feature. Everyone’s different. I know many people that focus on vintage, others that like horns, for me personally I go for sound quality. Just start with the most important area, and go from there.
It will work with no problems, but its not an optimal match for Vandersteen. If you find that you want to build a system around class D amps, You would probably be happier with a different speaker. Probably the best way to pick a system is to start with a must have, and then build around that. So, for example, class D is your must have, build a system around that feature. Everyone’s different. I know many people that focus on vintage, others that like horns, for me personally I go for sound quality. Just start with the most important area, and go from there.