Do you Bi-Wire, if you can?

I began with single wire and sound was excellent. I later upgraded to biwire.

To be completely honest, single wire for dollar spent was a more sensible option. I used identical brand and performance level both times so I think this was a fair test.

Anyway I‘m biwire now and enjoy the small performance advantage.

yes, my speakers allow for biwire. at the start I used a single pair of speaker cables + jumpers. The sonics were good.
Then, when I had some money, I bought a 2nd pair of speaker wires & did a shotgun run of 2 pairs of speaker cables per speaker. The sonics were vastly improved in the bass region. on this account i'm seconding Mattmiller "Two sets of runs always tightens things up!
Mattmiller"
In my case it was very apparent & successful. I won't be going back to a single pair + jumpers. FWIW. YMMV.

All speakers I have owned which can be bi, tri, quad wired have had explanations in their owners manuals about the benefits, and why the manufacture chose to design and build them this way. I have always taken advantage of this feature. My Matrix 800 are quad-wired. It does however cost more in ancillary equipment.

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From the Matrix 800 owners manual

Bi/Tri-wiring
Worthwhile improvements may be obtained by the progressive replacement of links by multiple loudspeaker leads which helps to minimise cable-borne interactions between crossovers.
Bi-wiring is strongly recommended as a minimum requirement.

If your speakers have dual terminals - The answer is yes - Why would you want use jumpers to almost do the same job?

I use Kimber 8PR in a 5/3 configuration. 5 wires for the woofer, 3 for the tweeter.