Admittedly, the balance connections were made with Hovland Music groove cable and the unbalanced everything from home brew silver and cotton to Cardas and Nordost types, so not like for like.
I have landed on the homebrew silver right now and I will try the balanced connectors on those for a definitive a-b.
The Io is phenomenal phono stage -even today- after all these years after its introduction.
I found that there are other more obvious things that could make a difference than the balanced connectors: tube choices, isolation , dual supplies and interconnect quality between the supplies and the Io.
Good luck with it an feel free to give it a try for yourself.