remove tubes before moving cross town?

Its ok for crosstown put not ok for uptown or downtown.

In case someone generalizes these answers, I might add that I would never transport an amp with a directly heated triode installed (45, 300b,etc.). I would definitely remove these tubes from an amp.

Tubes like those found in more "main stream" gear like that produced by ARC (i.e. 6922, 12AX7, 6550) are quite rugged and as an example, you’d never find a guitar player removing this family of tubes from their amp in order to transport it to a gig.

Cheers,
Thom @ Galibier Design

Inadvertently banging a tube and torquing the receptacles/pin clips in the socket will give you added work- more than simply pulling and replacing the tubes, you may have to tighten or repair the tube socket. In addition, even a relatively "smooth" ride in a car might cause some tubes to become (partially) unseated from the socket. I have found this to be the case even when lifting and moving a tube amp within my room- I always check that the tubes are seated fully.
Thom Mackris’ comments about guitar amps is true, but I seem to remember retainer clips on a lot of tubes for precisely that reason.

If I had to take the tubes out of my guitar amp every time I drove to a session, I'd give up. Maybe audio gear is more sensitive but I'd worry more about bending pins taking tubes in and out than I would a little driving.