When my audio system was in my living room (13x24), I had a pair of standmounts with sub woofer. The larger floor standing models I was considering had a law WAF (wife acceptance factor), in that smallish living room.
When I moved down to a 24x26 "man cave", I did upgrade to a pair of floor standing units (with a pair of sub woofers).
One thing to think about (if you go with stand mounted speakers and a sub woofer or two), integrating sub woofers can be really problematic in some rooms. Certainly that would not be as much of a factor with full range floor standing speakers.