Not to speak for George, but speaking for myself, yes, in some cases your ears will detect a difference, such as loss of dynamics or non-repeatable distortion. When you investigate with a 'scope, you will find high frequency trash being amplified along with the signal, which will compete for power allocation within the amp (causing loss of dynamics), or it may beat against the signal (causing distortion). Thus we have an aural effect which can be easily measured.
This method of connection (shield to the insensitive end) has been used in pro audio since Cain first cryo'd Able's tubes.