Where do I start-amp or speakers ?

Way to go, guys. Very helpful thus far. I have located a Cary 200.2 which is a possible start. It would good amp to build on; I had an AES tube preamp by Cary for a few years, and I really liked it.  I've had a pair of Quicksilver mini monos paired with a pair of gigantic Altec horns, which believe it or not sounded really nice. I did tubes for about a year until I came upon some Krell 250 monos then a pair of CS6's and I was off and running again.
 I heard Joseph Audios at the RMAC in Denver last year, as well as some Ryans(nice!) and a butt load of other speakers as well. I'm considering a trip to Chicagoland for Axpona this year;however, I did find the big audio fest to be confusing after awhile; stumbling off the elevators into hotel rooms crammed with gear, trying to find the "sweet spot" chair..
Thanks to all!

Speakers, always speakers.  The true heart of the system in my IMO, and absolutely the least "accurate" component in any system (well, some SET's...).  Speakers are all colored to some extent, find what you like there first, then move on.

MichaelJBrown

+1 to beginning with speakers, then choose the right amp to drive them. As Tim (above) points out, you have some homework to do -- what fun! I envy you...

Or I could save you the trouble. Send me the money and I'll choose for you :-)

Gasbose

Agree with the suggestions to pick speakers first, or at least vet their requirements, since that is the most subjective and variable part of the chain. My preference is to spend more on electronics than speakers though. There are a lot of enjoyable speakers for reasonable money (e.g. $2k) but electronics tend to scale in quality with price more linearly in m my experience. 

Tons of exceptions to above though. Matching ends up being the most critical factor and I’ve heard inexpensive setups that clicked and were really enjoyable for relatively little money.