Everything else being equal, should I expect better Spotify quality through wifi or USB?

I have heard that computers are noisy, and that their internal clocks can cause issues with music playback.  I was thinking that this would impact the playback through the USB cable.  Do you get the same jitter/clock issues regardless of if you go through a USB or wifi?  What about if I go through an ethernet cable from my wifi hub into the DAC?  Any difference to be expected?

Though I have no technical knowledge, I have found USB to be the weakest link for music-like you say jitter and clock issues.
Ethernet, for me gives the best results, with WIFI (and having a strong signal) a close second.
B

Not much chance they will sound different. But mind you, you are not only changing the connection variable (cable vs wifi) but perhaps also the protocol (usb vs optical/coax?).

Willemj:  Can you explain more?  If you change between cable for USB and wifi, where does optical/coax come into the picture?

I am just not sure what conections you are really comparing. A (wired?) computer with a usb cable into a usb DAC I understand and should give excellent results. Unlike some believe computers are an excellent source, and usb to an external DAC is fine. But how does your alternative actually look like?