The M5-HP is a battery biased active crossover designed for use with either Vandersteen speakers featuring built-in powered subs or Vandersteen 2W series subs.
They have internal jumpers that must be set to match the input impedance of your main amplifier(s). They can be ordered either in balanced or single-ended versions. As long as you don't switch from balanced to single-ended or vice-versa, these should work with almost any amp you might use now or in the future. Note that the 9-volt battery must be soldered in, and if you use lithium 9-volt batteries, expect to do this about once every 10 years.