static charge on the disk may cause induction in the electrical section after the optical system and may cause issues with the drive system if heavily ferrous. the drive system also has a motor that can be susceptible to the static charges. My feeling is the disk is rather benign (other then vibrations etc) in the system its what is effected around it that is probably what you hear.
I think the better solution would be to remove the CD reading all together and go solid state drives and store the data on a NAS etc. but many are reluctant to give up their CD players yet.