Short answer Mantaray is that you can mix and match to your hearts content. There is nothing that prevents it, and no reason not to.
THX is a performance standard, developed by Lucas Films to make sure that Return of the Jedi sounded the way the team at Skywalker Ranch (the Lucas recording studio) intended it to. Truth is it never really caught on with anybody in the consumer world but the manufacturers and the sales guys at the big box stores.
If you are concerned with compatibility, as long as you have the ability to decode THX you can play it back on any speakers. As Shiva points out, not much content is available anyway.
If you are setting up a home theater now, what you care about in the receiver is that it is HDMI 1.3 compliant, and has HDMI pass through. And that it can decode the Dolby Digital-HD AND DTS- Master audio formats that are being used on some BluRay tracks.
These are uncompressed tracks and they sound amazing.
Here is the salient part from Wikipedia:
The THX system is not a recording technology, and it does not specify a sound recording format: all sound formats, whether digital (Dolby Digital, SDDS) or analog (Dolby Stereo, Ultra-Stereo), can be "shown in THX." THX is mainly a quality assurance system. THX-certified theaters provide a high-quality, predictable playback environment to ensure that any film soundtrack mixed in THX will sound as near as possible to the intentions of the mixing engineer. THX also provides certified theaters with a special crossover circuit whose use is part of the standard. Certification of an auditorium entails specific acoustic and other technical requirements; architectural requirements include a floating floor, baffled and acoustically treated walls, no parallel walls (to reduce standing waves), a perforated screen (to allow center channel continuity), and NC30 rating for background noise.