I test and make cables daily. It is what I do. Yes, I test all manner of gauge, dialectic, twist, materials etc.., No, not just once or one combo.
It may be possible to find an outlier to my comment and in audio one must always leave the door of possibility open. I also know we all hear differently. My comment is based on my experiences, in general, with ICs. I did not take the time to post all my gauge testing in my post above.
Yes, the previous posts are in agreement with your comment about additional conductors being a good thing. This is a point of agreement. This is especially true when done in the DS arrangement. However, if using only one positive and one negative individually insulated wire there is a point when the thicker gauge is no longer a benifit. It actually becomes a sonic negative. I gave one example.