Does anyone play two pairs of speakers at the same time?

Way back, I played stacked large Advents with SAE amp.
They sounded OK but occasionally popped the stylus out of the groove.
Blew a few woofer surrounds too.
To this day I’m not fond of foam surrounds

Stacked Quads were/are(?) popular. And multi sub woofers are used. But outside of surround sound and home theatre, I don't personally know of anyone mixing different speakers simultaneously .

only while taking hallucinogens 

I have a two channel preamp and run one channel through a McIntosh MC302 amp and the other channel through a Bryston 4Bsst2 amp. One amp is connected to a pair of Pardigm signature S8V3 speakers and the other through vintage JBL L150 speakers. I have the right channel/left channel speakers pretty close together and spacing between the pairs of about 6 feet. This is an odd setup, mating more efficient modern Paradigm speakers with vintage less efficient JBL's so I adjusted the gain on the Bryston amp to match it better. I do like the sound of this setup, but sometimes go with individual pairs depending on the constellations or horoscope or something like that...

Not exactly the same thing but my AV receiver has a mode I think called "5 way stereo" or something like that.  Essentially, you tell it how many speakers you have and it spreads the stereo image among all of them.

I have some very nice L/C/R speakers  - Hales T1 monitors and a big Hales Transcendence Center channel.  I'd spread the stereo image among the L/C/R and it was super enjoyable.  Mostly it seemed to had a big thickening "heft" to the stereo sound, it just all sounded more solid, weighty and substantial.