@dr-john - I have been researching, auditioning and developing cables for the last 5 years.
There are some excellent geometries in development, but the issue with a specific geometry is that it seldom "translates" nicely to other cable functions - i.e. speaker, interconnect and power cables.
For example: the ribbon geometry (as used by Nordost) works nicely for IC's and for speaker cables, but presents problems when attempting to build a power cable.
Few manufacturers even attempt to use a successful geometry for all cables, so the mix and match method would generally be the best approach.
I have developed my own helix spiral geometry cables, which provide outstanding performance and actually reduces heat generated by the various components when used throughout the entire system. But again, when it comes to longer cable lengths, winding the helix spiral presents a problem.
One company that does utilize the same "design principles" for all of their cables is KLE Innovations. I have had the opportunity to audition many of their IC's and Speaker cables and found it advantageous to use their products only throughout my system, simply because they sounded superior to other commercial brands. The key to their design philosophy is keeping the neutral side of a components circuit at zero volts. Based on the results I have observed it would seem tat they are successful.
If you are not into DIY, then I would also recommend trusting your ears and try different brands.
Regards - Steve