I have built and sold USB cables for years trying all manner of conductors. Easy to hear the sonic character of pure silver vs. pure copper conductors in identical designs. One can also easily hear synthetic vs natural conductor coverings. My customers could easily tell when sending them two different USB cables to try and report back. Same general differences as found in analog cables. Materials have a sound regardless of design. They just do.
Is it possible some are less able to hear these differences? Yes indeed.
Is it possible some are less able to hear these differences? Yes indeed.