@dtximages I guess the place to start is by getting an SPL meter and checking your ambient noise level. I think as long as it is below ~45dB you'd be okay to run a measurement sweep as long as your speakers were outputting ~75dB - ~85dB, although it could get tricky at some frequencies due to the potential large swing in SPL.
If your ambient noise is really too much, you will need to find a time when it is quiet outside (a holiday?) or do something to block out external noise. Maybe just let your wife know you need like 10-15 minutes of noise one time at night. It should only take about that long once you are familiar with the process, and you can get familiar with it at some other times just by going through it, knowing it is a throwaway calibration.