Check out http://www.ielogical.com/Audio/SubTerrBlues.php for integration advice.
I ran a single 10" w TC-50s in 16 * 30 * 7 to good effect.
Adding good low end increases realism beyond all proportion. The operative word is good. As a composer friend opined on hearing my system "Every other subwoofer I've ever heard just boomed!"
Were I you, I'd opt for something with continous phase and a polarity inversion. Without them, integration will be problematic at best and impossible at worst.
Check out 2x ML800x as control is far more extensive than the RELs
Ignore everything millercarbon says.