This "directionality" at least as it applies to audio, would be easy to measure and/or quantify .... sort of like dielectrics, and once quantified, could be evaluated if within the realm of audibility
Using this logic, then all cables should sound similar since human hearing can hear any difference.
Most bulk circuit effects, i.e. resistance, inductance, capacitance are not even at the level to be audible (unless poorly designed/specified).
Again, this logic suggests that our audible ability is so poor we couldn't tell the difference. But it's been shown our hearing is highly acute.
The direction differences in those values, unless intentional, will be orders of magnitude below that .. or inaudible.
Certain an opinion and not a factual statement.