USB cables do make a difference. Even into my $3500 DAC. I have 5 cables here now and some are NIGHT AND DAY, it's not even funny how much difference can be made with a USB cable in a well set up and resolving system. I use an AudioQuest Diamond and have for 4 years. I keep testing others to see if one can best it for the same or a little more money but none have been able to up to $1000. I also have a $60 Audioquest Forest USB here and when that goes in? EEK. Sound shrinks, treble gets a tad more annoying, bass is less prevalent and the soundstage is not nearly as wide or deep. That is in comparison to the Diamond. I have a Nordost Blue Heaven and Heimdall USB here as well. Both of those can not get close to the Diamond. They lose air, extension and that cohesive sound that the diamond brings. The Nordost are thicker sounding. I also have a $20 cable here which sounds decent but you lose all of the magic that is so prevalent with the Diamond. I tried a Venom USB...warmer, thicker, more meaty mids but again, lose the ethereal character of the Diamond. I will probably keep my Diamond for life unless Audioquest betters it (unlikely).