I have Tonian Classic 12's with the PHY-12 inch Driver. The amplification will depend on your room and the type of music you like. I have used 45,2a3,300B,GM-70 SET's, a 15W Shindo Montille (EL-84), an Atma-sephere S30 OTL and a refurbed Dynaco ST-70 (EL-34) - all with good success. My current favorite amps to use with it are the Shindo and the Atma-sphere. The PHY driver is extremely revealing and while I generally love SET's, I find the tonal color becomes more exagerated with the PHY's than with other drivers I've experienced. The Shindo and Atma-sphere have a more neutral sound that seems to work well with the Tonians. The only amp that I paired with the Tonian that I really disliked was a 100W SS ICE based amp.
45 and 2A3's will be fine with intimate vocals, jazz and chamber music. I've found I wanted more power with larger orchestral works.
I bought the Tonians after hearing them at last years California Audio Show. To me they were one of the three best speakers at the show. However, I would strongly recommend that you audition PHY based speakers before you purchase them. Based on feedback I heard at the show people generally fall into the love or hate camp with not much middle ground.