Based on the reviews I have read, I do not consider the Nucleus overly expensive for what you get, and the build quality. If I ever needed to replace my Antipodes DX I would not hesitate to consider a Nucleus Plus with an internal or external drive.
Regarding, endpoints, the Nucleus can serve as both renderer and endpoint, as can my DX, and that will be great for many listeners. However, in addition to the reasons given above, the reason I use a separate endpoint is sound quality. I use Ethernet to connect my server to my endpoint and then use I2S to my DAC. Between my server and endpoint, I use two TP Link optical converters to optically decouple the Ethernet connection. The end result sounds better to me than running the whole thing through the DX only.