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As tubes wear, some problems can come up. One of the most common symptoms is a ringing sound. This is usually due to the tube becoming microphonic. Like its name suggests, a microphonic tube is picking up sound and amplifying it.
Dual triode preamp tubes like the 12AX7 really have two separate tubes inside one glass envelope. When the plate current draw of each triode is the same (as evaluated by our VTV testers), we refer to that as having balanced triodes. These may or may not also have the same gain on each triode but are still considered balanced.
12AX7 tube is a high gain dual triode tube found in many tube amps. Because of the high gain, the 12AX7 tube is often used in the V1 position of guitar amps, which has a lot of effect on sonics. It is the tube that defines the sound of your amp in a big way.