Moto Guzzi's feel very similar to the BMW horizontal flat twin vibrations, both are no-where near as smooth as he V Twin Ducati.For along time the 916 was my dream bike. Then a friend let me ride it and I never wanted to ride one again. It vibrated more than my Guzzi, the seat was hot and I nearly threw the thing on the ground trying to turn into an entrance ramp at slow speed; I was unprepared for its limited turn radius.
Actually you can get the Laverdas to be quite smooth (but not as smooth as a 90 degree or 180 degree twin). The trick on the triples is a computer controlled timing advance. It also helps to weight the ends of the handlebars. With the twins they are actually well-behaved on account of the pistons being 180 degrees apart when firing, and a well-weighted flywheel. Despite all that, they hold up extremely well.