Peter Lederman in Second Bout With COVID-19


I saw on Facebook late last night that Mike Fremer told one of his Audio Friends that he heard from Peter Lederman of Soundsmith that he is suffering his second round with COVID.  Peter said he has blood clots on his lungs. That is all the post said.  Here is hoping that Peter pulls through with a full recovery. 
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The pulmonary "emboli" of COVID are not really embolic in the true sense of the word; they are small clots that form in situ in the small vessels and capillaries of the lung, because the endothelial cells of those vessels bear ACE2 receptors that permit virus to directly infect them. This releases local clotting factors that promote the formation of the small clots or microthrombi in the tiny vessels that serve the alveoli or air sacs. Thus those air sacs may be functionally OK but they get no blood supply to pick up oxygen. These clots are very slow to resolve during recovery, which takes months, if indeed they ever go away completely.  I gather Peter is not in hospital (because he was able to respond to someone here) and is not requiring supplemental oxygen (because if he were, he would be in hospital), both of which are good things in his favor. However, if he knows he has clots in his lungs, he may well have a slightly reduced arterial oxygen or at least the characteristic confirmatory chest x-ray findings, which is best if it does not get worse.
I still wonder why he was not vaccinated at least a month or more ago. Maybe because with a prior history of COVID, he felt he did not need vaccination.  Actually, immunity due to vaccination with either of the RNA vaccines is probably superior to natural infection in providing protection against clinical illness.
Leronlimab, the monoclonal antibody recommended above, is probably worthless for COVID, certainly worthless for a person who already has significant pulmonary involvement. It was developed for HIV, which uses the CCR5 receptor.

Being an elderly male with Type A blood constitutes a risk group for severe disease per se.  Don't know about Type AB.
From all the above hard to know if Peter is or isn't in the hospital currently. Hopefully he's at home recovering and in good spirits.
Wishing him a speedy and full recovery.
@lewm , keeping up on it! Several small quips. I have one older woman S/P hospitalization for Covid on supplemental O2 at home. I have seen several large pulmonary emboli resorb completely over the years. These micro emboli should resorb completely. I do not think you can see them on a CXR or even a CT. We know they are there because we see them at autopsy. It is unknown what happens with healing because we do not do posts on living people. Eventually we will know for sure. I am also not convinced that the vaccine gives better immunity than the disease. That would fly in the face of just about every other viral disease we developed vaccines for. Keep in mind the pharmaceutical industry controls the media. What do you think all those wasted dollars on commercials is about.  Young people may actually be better off getting the disease. There are many antigens on the surface of that virus. This is nature's way of training good immune systems for the next sars virus that comes along. Also keep in mind that this disease is extremely minor in most people. People who have gotten both the flu and covid will tell you almost universally that the flu is worse. This is not to belittle the seriousness of this disease in the elderly, seriously obese people, and diabetics. 
One other small point. I have had over 200 patients with Covid and two people expire. I have not had anyone get the disease twice, this is more than likely a delayed response to the initial infection or a miss diagnosis somewhere down the line. The tests we have been using are not the most accurate. Many false positives.