Can Any Bookshelf Speaker Be Used Nearfield?

Back with another question, to improve my system and my education!

I've asked for and seen recommendations for speakers to be used nearfield.  (For me that nearfield is on a large desk, with 42" between left and right woofers and 40" from woofers to my ears).  

Now I'd like to learn about what makes a great, or poor, nearfield speaker?  I have a large desk and have room for large monitors.  Can all bookshelf-sized speakers be used nearfield?  Why or why not?  There are a ton of terrific monitor-sized speakers listed here for sale, but understanding why some would work or not work will really help me narrow down the choices.

Thanks in advance for your help!