The more revealing a system is, the more likely you will be able to hear any change when listening closely. The magnitude of the change and its positivity is subject to interpretation and exaggeration.
I have tried changes to internal vibration and isolation and the improvement depends on the piece of equipment. I find the turntable to be the most susceptible to external vibration and most improved by isolation. The amps had a more subtle improvement if any with isolation and coupling doesn't make sense because of ventilation concerns, and speakers in between with removing internal vibration by coupling it with a platform to a floor.
Anything that touches the equipment or the room acoustics can make a difference. Other hocus focus is environmental, not acousitical, and some may like that as well. It's just not an audio tweak. The degree and value is up to the listener and his budget.