That's a great question. Air is the medium that carries sound waves in a
listening room...unless your listening under water...where sounds waves
travel faster. Notice how sound is different on a hot clear day vs.
humid day vs. cold, cloudy, or especially foggy day?
Would it
make sense that the changes in atmospheric conditions in a room would
have an influence of soundwave transmission? No medium...no sound. Sound
travels through different mediums at different speeds. That's something
you can find with a Google search.
All that is patently obvious....the question was about "how much air is in the room" and exactly what effect there is when it changes and how that kind of change would occur "at any given moment" ( which implies a change over a very short time-frame ).
Cheers