I don't think Home Depot sells cable designs like Canare. Did you look at the wrap of the conductors or only the outer jacket?
I replaced my $2500 cables with Canare 4S11.
Electromagnetic interference (EMI) can radiate from these speaker lines directly into adjacent low voltage cables (i.e. microphone, video lines, etc.). Canare solves this problem by using a 4-conductor "Star Quad" configuration in all of our 4S Series speaker cables. Because every conductor is located the same distance from the center, the opposing magnetic fields are cancelled out. Attenuation of magnetic field radiation is superior when compared to a standard 2-conductor speaker wire.
I replaced my $2500 cables with Canare 4S11.