Advice on dedicated room

Hi everyone ,

I am going to start building my dedicated listening room in the basement soon and need some input. My ceiling is just under 8’ so would 2x4s be adequate for strength or would 2x6 be better? Second , I read an article where Robert Harley was building a new room and used the ISO wall system from acoustic sciences and was wondering if anyone here has used it and liked it. I will at the least use 2 layers of drywall and green glue. Lastly my space available is 15’x16 1/2’. I know that is too square and I can shorten the 15’ direction if needed but if we’re to put a 45 degree angle on two corners ( one corner is needed for access to another area) would that negate the “too square” aspect? Thanks for your input