I don't own the 2w, but I have a pair of 2Wqs. I also have an older Def Tech PF15 sub. Based on my experience, I would give a strong nod to the Vandy. My 2Wqs are powerful, yet tight and tuneful. The V2W should be an ideal compromise between a subwoofer oriented towards music and one oriented towards home theater. At $1550, you've got wood left over for a nice subwoofer cable.
Better still, if you have the space, I'd buy the 2Wq, which is intended mainly for music, and add it to your stereo mains. Take the $450 remaining and buy an inexpensive dedicated home theater sub. This will allow you to run your mains full range, and use the home theater sub for LFE and bass from the center and surround channels only. It's more or less what I do. Just note that you need to have preamp outputs and amp inputs to use the 2Wq.