What is the best USB cable under $500 for a natural presentation and good detail ?

This one has worked well for me. 

They also sell one which does not have the data and power runs split.  

I have only tried the "split" version.

I chose a Shunyata because it separates the data/power 

@mitch2 

What are the benefits you heard from using the split cable?

It is all system dependent. What may work for someone else may not work for you.  You'll never know what will work for you until you try it.  I was using an expensive solid core silver cable (in fact tried 2 different ones) for a DAC. These cables gave extra extension at both ends of the spectrum and added body. Then I changed my DAC to one with plenty of that extension and body and went back to an inexpensive solid core copper, Audioquest Pearl. Happy with that for the moment But it’s a continuing search for the best, not necessarily the most expensive! I suggest some experimentation first with cheap cables. Try the beautifully made Monoprice Monolith (solid core silver plated), for example. It may surprise you.  https://www.monoprice.com/product?p_id=33463

I can’t comment on splitting the power from the data as my DACs have provided power internally, not receiving any throught the cable.

@audioman58 This cable is fantasic I bought it on a whim several years ago and since then I've compared it to cables 20 times it's price and it's always come through and I'm talking hi-end systems.

I haven't tried it's big brother because I've been very content. It's a very detailed and exciting sound.