Ultimately you want a system that you enjoy. If equalization works for you, use it.
There are folks trying to build the best system possible, over the long term. I have been working on my for fifty years. There are paths that can get you off track. Equalization is one of them. It fixes issues but creates others. I have tried it several times and ultimately realized it created more problems than it solved. . Basically, I found that I needed to fix the problem directly instead of the symptom to get the most out of my components. If a component was too bright… getting a component that was not too bright got me much further along than did modifying the sound with a equalization… or whatever the problem was.
i agree with @ghdprentice as he stated above
that said, some folks have less time resources bandwidth, and thus a well designed fairly simple unit like a loki can fix some problems
but for a proper longer time answer for a dedicated audiophile really trying to optimize his/her rig, @ghdprentice 's approach is spot on imho