Three times with my current system build up.
1. adding AGD Audion mono blocks. For the first time I heard musician’s phrasing.
That is the most subtle and most profound.
2. adding a Lyra Atlas SL cartridge. The detail and imaging went threw the roof.
3. adding Townshend Podiums under my speakers. The speakers at least doubled in perceived price. In a real way, the most important.