I have two systems employing subs, one with DBA and one without.
The one with the DBA set up the fastest. I didn't have to mess with the sub locations and setting the amplifier controls was a breeze.
The other uses a single sub and I had to move it around quite a lot to find a spot that it could be heard at the listening position that was not also in the way. Where I wanted it and where it needed to be were quite different.
In both cases the subs are set to be operational below 50 Hz so no integration problems at all.