Hi Erik, I would think that you have the experience to do this well. I’ve built a few and they can be very enjoyable.
In general, for bass, the larger woofers work better... I used a 15 at one time and 2 12’s once and 2 10’s another....
Try to keep your QTS between .5 and .8, My experience says look for a .6 and keep it under .8 if you can. VAS and XMax matters. It all depends on the room, stay mindful of response curves, remember that you are now firing from the rear also and room boundaries come into play more easily. If you use a mid, still look at QTS. It is less critical as you move up in frequency, but I would still try to find .5 to .6 QTS.
If you get them built, pull them out in the room listen and slowly move them back toward the walls little by little until you find the boundry reinforcement that fits your taste. Initially, you may find that you don’t have much taste. If you like, don’t hesitate to add another woofer, even a 15, air movement is the key to get bass moving, but stay aware of your room and boundaries that you may have to deal with. I have no doubt that you can pull this off. Use your experience and your ears, you’ll be fine.