What is the science behind audiophile fuses?

     "Louis Pasteur's theory of germs is ridiculous fiction."  (Pierre Pachet, Professor of Physiology at Toulouse , 1872) 

     "The abdomen, the chest, and the brain will forever be shut from the intrusion of the wise and humane surgeon,"  (Sir John Eric Ericksen, British surgeon, appointed Surgeon-Extraordinary to Queen Victoria 1873)

      "The super computer is technologically impossible.  It would take all of the water that flows over Niagara Falls to cool the heat generated by the number of vacuum tubes required." (Professor of Electrical Engineering, New York University)                        

      "There is no likelihood man can ever tap the power of the atom."  (Robert Millikan, Nobel Prize in Physics, 1923)

      "Man will never reach the moon regardless of all future scientific advances." (Dr. Lee DeForest, Father of Radio & Grandfather of Television)

      "Heavier-than-air flying machines are impossible!" (Lord Kelvin, president, Royal Society, 1895) 

      "The bomb will never go off.  I speak as an expert in explosives."  (Admiral William Leahy, re: US Atomic Bomb Project) 

     When the steam locomotive came on the scene; the best (scientific) minds proclaimed, "The human body cannot survive speeds in excess of 35MPH."

      Until recently (21st Century); and the advent of the relatively new science of Fluid Dynamics, the best (scientific) minds involved in Aerodynamics, could not fathom how a bumblebee stays aloft. 

     Often; Science has to catch up with the facts/phenomena of Nature and/or, "reality" (our universe). 

     I haven't been in school since the 60's, but- at Case Institute of Technology; the Physics Prof always emphasized what we were studying was, "Electrical THEORY."         He strongly made a point of the fact that no one had yet actually observed electrons (how they behave on the quantum level) and that only some things can really be called, "LAWS." (ie: Ohm, Kirchoff, Faraday)   

                  PERHAPS: that's changed in recent years and I missed it?

This reminds me of Elizabeth Holmes!

I did not know that marketing is science. Then I am a scientist, cool. 😎

@reimarc ,

Told ya...

Thanks to everyone and your at times spirited responses. And no, I am not a "puppy seal" asking apparently innocuous questions only to stir up the pot. I am a scientist and a curious one at that. I learned that a fuse is indeed part of the circuit, in series, not in parallel: not the signal circuit itself but the part that supplies the power for proper operation. I also learned that the fuse-material itself (alloy, etc.) shares the characteristics of a resistor, one that "blows" when too much current flows through it. As such, it would make sense, that in a highly dynamic amplifier setting, for split-seconds a sub-optimal level of current would be available to amplify the signal in true fidelity. In so far, the use of materials that have less resistance and yet still fulfill their safety-valve function would make sense - at least theoretically. But what about audio practice? Will one actually HEAR the difference? Or let me re-phrase: will someone with average ears (in my case age-relatedly compromised) and a sub $50K system with enjoyable but probably not stellar performance hear such a difference?

Yesterday I went to the annual "Exotics on Broadway" exhibition in Seaside, part of the world-famous Monterey Car Weekend. Exotic supercars and so-called hyper-cars, some of them costing multiple millions of Dollars, are on public display there for everyone to admire and talk to the developers/dealers for free. If you are into state-of-the-art automotive "art", that’s a place not to miss. I do love looking at these cars, I admit. But driving one? My Tesla S leaves still many of them in the rear mirror, and doing so without the ear-splitting noise of a 1,500 horsepower engine. The same goes for my stereo set-up: I tremendously enjoy what I got in terms of delivering listening joy every night - with Bussmann fuses, mind you. But I also know, that certain tweaks can indeed make a noticeable difference: I recently replaced my Mogami XLR ICs with all-silver, shielded ones from Taiwan, and yes: even I with my compromised hearing could immediately hear the difference; and no: no confirmation bias here, which I thoroughly understand on a professional level, and in any case, the new ICs were rather affordable. So, would I be able to hear such a difference by replacing my Home-Depot fuse (which came standard with my all-tube preamp)? Perhaps, but I don’t really think so; also, because exotic fuses - if they have their audio reason to exist - would probably exerting their "magic" in an amp rather than in a pre - and probably in a much more sensitive, i.e. costly, one, than the ones I use. But that I don’t really know. What I do know, however, that as scientists we always stay on the shoulders of giants (Feynman citation, I believe), and yes, a fundamental characteristic of good science is not to be dogmatic (we do not "believe" in science), but critical nevertheless. Let the data speak. In my case, the "data" are being delivered to my analytical brain through my ears, and not through a sophisticated measuring device, which might indeed pick up differences from audiophile fuses, albeit - at least in my case- inaudible ones. So be it: I "measure" performance along the coordinates of enjoyment and cost, like - I am sure - do many of you. And with the data at hand, and your delightful and sometimes informative comments, I will probably abstain of paying hundreds of $$ for a tweak that I might not be able to hear with the gear, and ears, I got. Again, thanks to all!