I used to output USB from my IMac to my DAC... Sounded OK to me. Then I got a SOtM SMS200 Ultra network streamer to feed my DAC. Everything opened up more and became both better controlled and Wider/Deeper at the same time.
Every once and awhile, I got back to iMac > USB > Dac for a few days to reconfirm the rightness of my now 4-year old choice. And it has always been a joy to return to the streamer. The iMac still runs the Roon Core, but the music comes via the SMS 200 ultra via the network. I also now use HQ Player and the SOtM comes stock the the HQP NAA built in.
I’m very happy with the SOtM streamer, but more than that I am just recommending the addition of a network streamer/bridge of sufficient quality rather than feeding your DAC from your Mac Mini.