The room has a significant effect on sound. This has been known a long long time, nothing new here.
I am sure that is true, but so does the equipment.
I went from a somewhat "cluttered" living room with unequal side walls (meaning no sidewall on one side depending upon which end I had my speakers at), andalso depending upon which end my speakers were at, the front wall/or rear wall had an open hallway leading into/out of it . . . so, as I was saying, I went from this room to a small spare bedroom with different stuff on one sidewall than the other (bookshelf on one sidewall and gunsafe and equipment shelves on other sidewall) and bookshelves completely covering what is now the backwall. This turned into a very nearfield room. I thought I would enjoy the intimacy I thought I would achieve in the small room, and I actually do enjoy the fact that there are no distractions back there, but I do find that I miss the open feeling and ability to crank up some volume in the living room. But by moving some stuff out of my current small room and spending some time playing with speaker positioning and listening in the dark I can appreciate that with good source material that the soundstage that is created actually seems to extend beyond the boundaries of the room.
All of that was to say that through this I realize that the room does have a dramatic effect on the the sound that is reproduced.
But: in both flawed rooms I have played around with different pieces of equipment (digital front ends, preamps, amps, cabling and speakers) and in both flawed rooms I have heard differences in sound quality (both good and bad differences) as I played around with different gear.