I run without preamp, directly into Nuforce 9SE V3. The Metrum is with a 14VA powersupply. Non-fatiguing is definitively not at the expense of detail. Initially, there was almost too much detail, detracting somewhat from what Sarjan might call "Gestalt" - but with time, the brightness settles, and the tome becomes more balanced, maybe even "lush". I have listened but not critically compared the RWA Isabella (this includes preamp), Nuforce HDP, Ack Dac, Promitheus Dac and Weiss Dac2. Those are all good products. The Metrum however is in a different league. I have not listened to other acclaimed products, such as PDX, Lampizator, Bryston etc. I have to admit, I am not pursuing the "holy grail", but want have a system where I can completely relax and forget about equipment (which is hard enough to get...). A long time ago, I used an Alphason Sonata with a Garrott P87 cartridge, Spectral DMC12 and DMA50 into Quad ESL63. I was happy then, and I am now. I hope it will last.