To loom or not to loom?

Ladies and Gentlemen.

I am asking for your experiences in running a complete loom of one brand of cable, experiences not opinions and conjecture please.

I have 2 systems with interconnects from DH Labs and Zavfino, Speaker cables from Zavfino and Wireworld. Power cables are a mishmosh of LessLoss (digital front end) Zavfino (tubes), SR Research SS monoblocks, all great quality cables. 

Should I look at consolidating each system to a specific brand and model of cables or is this a fool's errand? 

Again if you do not have specific experiences please refrain from posting gibberish and innuendo.