**Smoking integrated tube amp, advice needed:

Ayon , machined chassis not sheet metal , Critical for any good tube amps 

Lundahl chokes,and transformers, Mundorf coupling capacitors 

gold copper tube sockets which are much better then most cheap gold brass 

and most important also microprocessor controlled. Most amps average the power tubes output.Ayon monitors and adjusts each tube for wear ,when a tube goes,

a red led comes on and if you are not in the room shuts it down  you just 

replace the tube ,and hit the button to re bias  all the tubes.

in a regular tube amp ,if a tube has runaway voltage and blows ,it can take out a transformer or other parts.made in Austria,not China 

I used to own a pair of ARCs that one or the other would routinely blow a grid resistor, but it was never as bad as what you have described (no smoking and such).  If you are feeling adventurous, unplug it and put it on a work area and pull the bottom off and see if you can identify any smoked electrical components.  Be careful around the capacitors, you might want to get a hold of a shunt to manually make sure they are discharged (although if it has been turned 'off' for a couple of days I would think that they would be).

Someone mentioned "runaway voltage" and I now have a Cary amp and a coupling cap went out and i did get a run away bias going on.  I imagine the tubes got pretty hot in the short time it operated without me catching it, but again:  the tubes were not "glowing red" and no smell of smoke.  If I hadn't have caught it, maybe they would have after a short while, so perhaps you have a run away bias going on, but I don't know anything about bias and preamp tubes and I wouldn't think it would happen "almost imediately."

When you say:

I connected the black side of each speaker cable to the white amp input, and the red side to the red 8 ohm tap of the amplifier.

are those the ONLY four binding posts for speaker cables that are on back of that unit?

Your Story is very much in keeping with adice given a long time ago,  in relation to be disciplined towards a safety attitude around tube equipment.

I was informed of Red Valves and the need to have eyes on Tube Equipment at Power On and in use and double check shortly after Power Off.

I am vigilant about this attention given.

You are lucky to have discovered this condition developing, and getting it stopped asap.

The repair is beyond the usual skill set and will need a EE, preferably one that has Valve Experience.  

Other than misusing the term input when you meant output, your setup sounds perfectly all right…assuming the white speaker terminal is labeled negative or 0.  If the amp is set up correctly for your voltage, it was defective.  You should return it.

@fugazikid1991 Sounds like the amp was damaged prior to your placing it in your system. Was the shipping box damaged?