I had those speakers in my system and would not recommend tubes to drive them and especially not in a room the size of yours (Thiels in general are not tube-friendly speakers). I drove them with both a robust 100Wpc (roughly doubles into 4 Ohms) and 200Wpc amp and the 1.6es opened up more with the more powerful amp. If anything I’d go with a hybrid integrated like a Unison Unico, etc. Just my experience FWIW, and great speakers BTW.