Depending on your speakers a true end game amplifier that you wouldn't want or need to ever upgrade is the SE84UFO25 by Decware. Two of the most musical watts out there. The Decware owner actually made the first amp for himself as a state of the art SET amplifier. It turned out so good that he offered at over three times the cost of the SE84UFO and now the Decware backlog is an over three year wait time.
It's a niche product for people with speakers in the 100DB sensitivity range but is truly a piece of equipment that you can inexpensively tube roll and tune for the specific sound characteristic you desire.