Is there usually a dramatic difference between $5k and $10k cartridges ?

Yeah, some do it right. Later Pink Floyd used Van den Hul cables. They needed two miles of them, as Gilmour said, and they got it.

"some do it right” - who does not? list would be welcome! :-) 

Not to sound like a smart ass, but has anyone actually answered the OP question with experience or just speculation? 98% of the answers are BS. Some good BS but am I wrong 🤔 

I think, some did answer with experience. Besides, the interpretation of "dramatic difference" can vary. But there is some BS, no doubt.

Inna correct, 1 or 2 but the rest BS 😜.  I don't have the funds for cartridges of that level however,  when I went from a Dynavector 20x2L to a Hana Umami Blue it was a very noticeable difference.  I can understand at that price point but does the laws of diminishing returns kick in at 5K?