Is there usually a dramatic difference between $5k and $10k cartridges ?


In top of the line or near top of the line system.

inna

interpretation of "dramatic difference" can vary

Likely some “emotional” connection to the “perceived” sound change which both can vary per each individual 

Yes but you have to be careful. Many cartridge manufacturers have a bit of "house sound" so do your research. 

The comment about very cheap cables in recording studios is doubtful, but even if true is meaningless. It is about getting the most from the software. Same with statements about AC to your outlets.

The big question is can you enjoy your $10K cartridge more than I enjoy my $2K cartridge? I ask because I have never enjoyed a system more than my $100 Sears Silvertone suitcase stereo when I was in college. It must have had a steel stylus. Smoke a joint and listen to Stravinsky's Firebird with my girlfriend next to me in bed. I will never have that musical enjoyment again, but I do still get deeply into music sometimes. And when I'm in that musical mood, $!K cartridge, $2K, $50K, it wouldn't matter. Just give my porous brain the music.