I'm not real sure that I understand your question. If you are using a Squeezebox as a front end and your Squeezebox is capable of playing 24/96 files, then your only limitation is going to be the amount of bandwidth that your wireless system can support.
In my system, the only part that iTunes plays is to help me maintain my music library. There is no real direct interaction between iTunes and my Squeezebox. My Squeezebox just happens to pull the music files from the directory that iTunes saves my music files to. In other words, iTunes does not need to be running in order for the Squeezebox to be able to pull files from your hard drive.
Unless I'm mistaken, Squeezebox is setup for wireless. If so, then all you need is a wireless router that is fast enough to transfer your music files.
In my system, the only part that iTunes plays is to help me maintain my music library. There is no real direct interaction between iTunes and my Squeezebox. My Squeezebox just happens to pull the music files from the directory that iTunes saves my music files to. In other words, iTunes does not need to be running in order for the Squeezebox to be able to pull files from your hard drive.
Unless I'm mistaken, Squeezebox is setup for wireless. If so, then all you need is a wireless router that is fast enough to transfer your music files.