Just like to add my experience with Sakura cable. I've obtained the best sound by running the .4 cable on the positive/hot and .6 on the negative/return, both single stranded. Some of you are aware that there are two 47 Labs cables, one that is slightly thicker than the other.
A friend of mine, while in Japan went over to Junji Kimura's (designer/builder of all the 47 Labs gear) house and listened to his setup. While there Mr. Kimura told him that he prefers not to use multiple strands of cable. (Even on his power cords!) Mr. Kimura said that multiple strands break the signal up which affects the "timing relationships" in the music. I'm not sure if this is exactly what he meant because, even though my friend speaks fluent Japanese, true meanings get lost in translations.
A friend of mine, while in Japan went over to Junji Kimura's (designer/builder of all the 47 Labs gear) house and listened to his setup. While there Mr. Kimura told him that he prefers not to use multiple strands of cable. (Even on his power cords!) Mr. Kimura said that multiple strands break the signal up which affects the "timing relationships" in the music. I'm not sure if this is exactly what he meant because, even though my friend speaks fluent Japanese, true meanings get lost in translations.