I don't know about fancy lift products, but there is usually benefit to keeping the cables off of the floor. Especially carpet over concrete. It could be a capacitive interaction, I don't really know. Lifting my speaker cables did result in a bit more blackness in the background.
We Galibier owners have often demonstrated the effect of lifting the battery power supply off of the floor. There is no change in speed, but there is a sudden effortlessness when the battery is lifted. It seems that after these batteries have been sitting on the carpet for a while they also build a little capacitance. It can be demonstrated again, but the battery has to be used sitting on the floor for a while to build the effect back up.
Vibrations in cables do matter, but I don't think any of our stereos can put out that much energy to do this through signal power. ;-) However, try tapping on an interconnect lightly and see if you hear it through the speakers. This tells me the cables just need to be left alone, not nailed to the wall or something.