Theoretically Yes.
It can happen that you won't have to break them in but that's rare.
It can happen that you won't hear the difference between cables that had been running for 200...800 hours and brand new.
A conductor's break-in process is to direct electrons to the "right path" with minimal energy loss.
In bunch of cases breaking-in cables with your home equipment will bring you no success throughout long time of listening since breaking-in process might require much higher current to "straighten out" dielectric or semi-conductor nature inner impurities randomly residing inside the conductor.
It can happen that you won't have to break them in but that's rare.
It can happen that you won't hear the difference between cables that had been running for 200...800 hours and brand new.
A conductor's break-in process is to direct electrons to the "right path" with minimal energy loss.
In bunch of cases breaking-in cables with your home equipment will bring you no success throughout long time of listening since breaking-in process might require much higher current to "straighten out" dielectric or semi-conductor nature inner impurities randomly residing inside the conductor.