Your digital or video sources are connected to the prepro, analog sources (including DAC outputs from digital sources)to the 2ch pre. The amp (or amp channels) feeding the L/R mains are fed from the main-outs of the 2ch pre, the amp/channels feeding center and surround speakers are fed by the outputs on the prepro. If the 2ch pre has a processor loop, you'd hook up the L/R main-outs from the prepro to those preamp inputs and simply select that source when viewing sources connected to the prepro. Selecting this processor source bypasses all the pre's circuitry including the volume control. If you do not have a processor loop/input, you can use the tape loop input. However, this means the 2ch pre's volume control is still in the circuit as well, so to maintain correct calibration of the multi-channel setup, you must pick a convenient volume setting on the 2ch pre (say top dead center), and do your calibration and then all subsequent viewing/listening thru the prepro at this same 2ch pre volume setting. Make sense? There's a thread originated by Thomas in Preamps/amps entitled "Well, another preamp/HT integration question ..." you may want to read. Good luck!
Tim
Tim